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    Anesthesia Considerations 

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    NK-1 Receptor Antagonists 

     

    Aprepitant 

     

    • 40-80mg PO within 3 hours of induction of anesthesia 

    • Routine use not yet established 

    • Appears to be more effective than ondansetron in preventing PONV in the first 24-48 hours 

     

    Adapted from Anesth Analg. 2014 Jan;118(1):85-113