Anesthesia Considerations 

Bicarbonate Therapy 

 

 

• Do NOT use sodium bicarbonate therapy to improve hemodynamics or to reduce vasopressor requirements in patients with hypoperfusion-induced lactic acidosis with pH ≥ 7.15 

• Possible adverse effects of uncertain clinical significance:

  • Sodium & fluid overload

  • ↑lactate & Paco2

  • ↓serum ionized calcium

 

 

Adapted from Surviving Sepsis Guidelines 2016. Critical Care Medicine: March 2017 - Volume 45, Issue 3, p 486–552