Bicarbonate Therapy 

 

 

  • Do NOT use sodium bicarbonate therapy to improve hemodynamics or to reduce vasopressor requirements in patients with hypoperfusion-induced lactic acidosis with pH ≥ 7.15 

  • Possible adverse effects of uncertain clinical significance:

    • Sodium & fluid overload

    • ↑lactate & Paco2

    • ↓serum ionized calcium

 

 

Adapted from Surviving Sepsis Guidelines 2016. Critical Care Medicine: March 2017 - Volume 45, Issue 3, p 486–552